A canine case of hypertrophic pulmonary osteoarthropathy with atrophied parathyroid glands and lowered plasma vitamin D metabolites  [1995]

A male 10-year-old mongrel dog with swelling of all the limbs and lameness was diagnosed clinically and radiographically as hyupertrophic pulmonary osteoarthropathy, showing irregular border of the humerus, radius and ulna, periosteal proliferation of the femur, peritibial and perifibular new bone formation and an irregular surfaced mass in the thorax. Hypocalcemia, hyperphospheremia and lowered plasma vitamin D metabolites were revealed. Histopathology demonstrated the atrophied parathyroids, porosity of tibial compact bone and infiltration of bronchioloalveolar carcinoma in the lung, especially right diaphragmatic lobe, with heat worm embolism in some pulmonary arteries