Written Paper

Hepatopotective Effects of Black Rice on Superoxide Anion Radicals in HepG2 Cells  [2006]

Shim, S.I. (Gyeongsang National University, Jinju, Republic of Korea) Chung, J.W. (Korea Research Institute of Bioscience and Biotechnology, Daejeon, Republic of Korea) Lee, J.M. (Nambu University, Gwangju, Republic of Korea) Hwang, K.T. (Nambu University, Gwangju, Republic of Korea) et al.

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Cyanidin 3-glucoside (C3G) isolated from black rice was investigated for hepatoprotective effects in HepG2 cells under oxidative stress. When an increase in the production of reactive oxygen species (ROS) was induced by gramoxone, cell viability was drastically decreased by 42%. However, in the presence of C3G, no hepatocytic damage was observed in HepG2 cells treated with gramoxone. C3G was found to manifest a stronger scavenging effect (91%) on superoxide anion radical (O₂-) than any of the other natural and synthetic antioxidants.

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Food Science and Biotechnology

ISSN : 1226-7708