The Protective Effect of Chlorophyll a Against Oxidative Stress and Inflammatory Processes in LPS-stimulated Macrophages  [2007]

Park, J.Y. (Inje University, Gimhae, Republic of Korea) Park, C.M. (Inje University, Gimhae, Republic of Korea) Kim, J.J. (Inje University, Gimhae, Republic of Korea) Noh, K.H. (Inje University, Gimhae, Republic of Korea) et al.

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This study was designed to investigate the suppressive effect of chlorophyll a on nitric oxide (NO) production and intracellular oxidative stress. In addition, chlorophyll a regulation of nuclear factor (NF) κB activation and inducible NO synthase (iNOS) expression were explored as potential mechanisms of NO suppression in a lipopolysaccharide (LPS)-stimulated macrophage cell line. RAW 264.7 murine macrophages were preincubated with various concentrations (0-10 ㎍/mL) of chlorophyll a and stimulated with LPS to induce oxidative stress and inflammatory response.

Other subjects

  • stress
  • nitric oxide
  • oxyde nitrique
  • iNOS expression
  • macrofagos
  • oxidation
  • macrophage
  • chlorophyll a
  • inflamacion
  • oxido nitrico
  • macrophages
  • oxidacion
  • inflammation
  • oxydation
  • estres

From the journal

Food Science and Biotechnology

ISSN : 1226-7708