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Antioxidative and Hepatoprotective Effects of Lythrum salicaria  [2009]

Lee, S.E., National Institute of Horticultural and Herbal Science, RDA, Eumsung, Republic of Korea Park, C.G., National Institute of Horticultural and Herbal Science, RDA, Eumsung, Republic of Korea Ahn, Y.S., National Institute of Horticultural and Herbal Science, RDA, Eumsung, Republic of Korea Son, Y.D., National Institute of Horticultural and Herbal Science, RDA, Eumsung, Republic of Korea et al.

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Abstract
Several parts of Lythrum salicaria were used for this study. Scavenging activities on radicals, inhibitory activity on linoleic acid peroxidation and total phenol contents of extracts from root, flower, and aerial part were evaluated. Flower and root selected from in vitro assay were subjected to in vivo assay on CCL₄-induced liver injury rat model for two weeks. Carbon tetrachloride intoxication on rats produced large amounts of hepatic lipid peroxidation product, thiobarbituric acid reactive substance (TBARS) compared with normal rats. Treatment with root extract of L. salicaria (LSR) showed effective inhibitory activity on lipid peroxidation product. Administration with LSR extract significantly alleviated CCL₄-induced increase in GPT activity which were more effective than silymarin. The results of this study suggest that root and flower of L. salicaria have antioxidant and liver protecting activities, and root part is the most effective candidate to develop a new functional material.
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Other subjects

  • Hepatoprotection
  • antioxydant
  • antioxidants
  • Lythrum salicaria
  • Carbon Tetrachloride
  • antioxidantes
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Other information

Language : English

Type : Directory

In AGRIS since : 2011

Volume : 17

Issue : 1

Start Page : 1

End Page : 7

All titles :

" 털부처꽃의 항산화 및 간장보호활성 "

" Antioxidative and Hepatoprotective Effects of Lythrum salicaria "