Effect of stress following vaccination (Avinew) against newcastle disease inbroilers  [2005]

Aslam, A. Jamal, A. Khan, S.A.,University of Veterinary and Animal Sciences,Lahore (Pakistan). Dept. of Pathology

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The present project was designed to find out the degree of stress andimmune status in response to vaccination (Avinew) against Newcastle (ND) and alsoto know the effect of two therapeutic agents, i.e. multivitamin and aspirin, onefficacy of the vaccine. One hundred and sixty day old broiler chicks weredivided into four groups i.e. A, B, C and D, each group having 40 birds. Group Awas kept as control, B was vaccinated but not medicated, group C was givenmultivitamins along with vaccine for 3 post vaccination days and group D wastreated with aspirin for 3 post vaccination days. Blood samples from 10 randomlyselected birds were collected on days 1st, 14th, 28th, and 42nd for detection ofantibody titre against Newcastle disease virus (NDV). Blood samples were collectedfrom 10 randomly selected birds of each group after 24, 48, and 72 hours ofvaccination for study of heterophil/ lymphocyte ratio and estimation of serumbiochemical substances (Protein, glucose, and cholesterol). At the end of theexperiment, adrenal glands of 10 randomly selected birds from each group wereexamined for adrenal/body weight ratio, gross/ histopathological lesions andeconomics of the flock was also calculated, " Avinew " (freeze dried live VG/GAvaccine) against ND, activated the immune response of the chicks with out anysignificant stress. It provided a reasonable and persistent antibody titre.Multivitamins supplementation showed immuno-potentiating effect and also positivetrend in gr
owth traits. The effect of aspirin on immune response and weight gainwas variable.

Other subjects

  • stress
  • immune
  • newcastle disease
  • broiler chickens
  • vaccination

From the journal

The Journal of Animal and Plant Sciences (Pakistan)

ISSN : 1018-7081