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The inhibition of some cancers and the promotion of others by folic acid, vitamin B12, and their antagonists.  [1983]

Herbert V. National Diabetes Information Clearinghouse (USA). National Institute of Arthritis, Diabetes and Digestive and Kidney Diseases (USA). [Corporate Author]

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Abstract
A technical review suggests the hypothesis that folate or vitamin B12 deficiency (or any other cause of failure to methylate DNA and/or RNA) can activate malignancy by hypomethylation of oncogenes, and that the methylating oncogenes can inhibit malignancy by making them dormant. Specific attention is given to: the effects of folate deficiency; the role of vitamin B12; and studies on suppression testing to measure folate and vitamin B12 deficiencies in terms of slowing DNA synthesis.(wz).
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Other subjects

  • vitamine b12
  • acido folico
  • antagonism
  • vitamin b12
  • carcinoma
  • acide folique
  • carcinome
  • antagonisme
  • folic acid
  • antagonismo
  • vitamina b12

From the journal

Bristol Myers nutrition symposia

Other information

Language : English

Type : Journal Article

In AGRIS since : 2012

Volume : 2

Extent : v.273-287

All titles :

" The inhibition of some cancers and the promotion of others by folic acid, vitamin B12, and their antagonists. "