Written Paper

Cardiovascular effects of n-3 fatty acids  [1988]

Leaf, A. Weber, P.C.

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A detailed technical overview summarizes and discusses available evidence concerning the effects of fish oil n-3 polyunsaturated fatty acids (PUFA's) on reducing cardiovascular disease risks. Attention is given to: the characteristics and metabolism of n-6 and n-3 PUFA's and the effects of n-3 PUFA's on plasma lipid profiles; the role of n-3 PUFA's in reducing atherosclerosis risk; possible protection of n-3 PUFA's during myocardial infarction; the relative importance of eicosapentaenoic vs. docosahexaneoic acids; and appropriate intakes of n-3 PUFA's. The potential adverse health effects from ingesting fish oils also are discussed.(wz)

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New England journal of medicine (USA)

ISSN : 0028-4793