Journal Article
Effects of Keumsa Sangwhang (Phellinus linteus) Mushroom Extracts on the Natural Killer Cell Activity in Human [2006]
Eom, S.Y. (Chungbuk National University, Cheongju, Republic of Korea); Zhang, Y.W. (Chungbuk National University, Cheongju, Republic of Korea); Kim, N.S. (Chungbuk National University, Cheongju, Republic of Korea); Kang, J.W. (Chungbuk National University, Cheongju, Republic of Korea); et al.
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A randomized, double blind, placebo-controlled human intervention study involving 62 healthy volunteers was performed to investigate the effects of Keumsa sangwhang (Phellinus linteus) mushroom extracts (KPLE) on natural killer (NK) cell activity in peripheral blood. The volunteers were randomly distributed into two groups, one receiving KPLE (3.3 g/day) and the other a placebo by oral administration for 8 weeks. In this study, the number of NK cells did not increase with KPLE administration, however the cytotoxic activity of NK cells against the Jurkat leukemia cell line increased significantly.
