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The Indian Council of Agricultural Research (ICAR) is an autonomous organisation under the Department of Agricultural Research and Education (DARE), Ministry of Agriculture, Government of India. Formerly known as Imperial Council of Agricultural Research, it was established on 16 July 1929 as a registered society under the Societies Registration Act, 1860 in pursuance of the report of the Royal Commission on Agriculture. The ICAR has its headquarters at New Delhi.

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Journal Article

Artículo de revista

Ultrastructural changes in kidneys and liver in experimentally induced ochratoxicosis in wister rats.  [2004]

Satheesh, C. C.; Sharma, A. K.; Prasanna, K.; Dwivedi, P., Indian Veterinary Research Institute, Izatnagar (India);

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Ultrastructural studies of the liver and kidneys of rats at 4 and 8 weeks feeding of 4ppm ochratoxin A (OTA) revealed that mitochondria of proximal convoluted tubules (PCTs) in the kidneys of the toxin fed rats were more severely affected, as evidenced by mitochondrial swelling, vacuolation, ring forms, pleomorphism, and disintegration and loss of cristae. The intercellular junctions of PCT epithelial cells were widened and there was complete loss of microvilli. In liver, hepatocytes revealed pyknotic nuclei with increased heterochromatin, degranulation of rough endoplasmic reticulum and vacuolation of cytoplasm besides changes in mitochondria. The changes became more pronounced with increase in duration of toxicity. It may be concluded that OTA causes alternations primarily in mitochondria of renal PCT cells and liver hepatocytes.
Publicación
Indian Journal of Veterinary Pathology (India)
ISSN : 0250-4758

Información bibliográfica

Idioma:
English
Tipo:
Summary
En AGRIS desde:
2009
Volumen:
28
Edición:
1
Página inicial:
21
Página final:
24
Todos los títulos:
"Ultrastructural changes in kidneys and liver in experimentally induced ochratoxicosis in wister rats."@eng
Otro:
"Summary (En)"
"8 ill., 21 ref."
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Información bibliográfica

Idioma:
English
Tipo:
Summary
En AGRIS desde:
2009
Volumen:
28
Edición:
1
Página inicial:
21
Página final:
24
Todos los títulos:
"Ultrastructural changes in kidneys and liver in experimentally induced ochratoxicosis in wister rats."@eng
Otro:
"Summary (En)"
"8 ill., 21 ref."