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The Indian Council of Agricultural Research (ICAR) is an autonomous organisation under the Department of Agricultural Research and Education (DARE), Ministry of Agriculture, Government of India. Formerly known as Imperial Council of Agricultural Research, it was established on 16 July 1929 as a registered society under the Societies Registration Act, 1860 in pursuance of the report of the Royal Commission on Agriculture. The ICAR has its headquarters at New Delhi.

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Journal Article

期刊文章

Ultrastructural changes in kidneys and liver in experimentally induced ochratoxicosis in wister rats.  [2004]

Satheesh, C. C.; Sharma, A. K.; Prasanna, K.; Dwivedi, P., Indian Veterinary Research Institute, Izatnagar (India);

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Ultrastructural studies of the liver and kidneys of rats at 4 and 8 weeks feeding of 4ppm ochratoxin A (OTA) revealed that mitochondria of proximal convoluted tubules (PCTs) in the kidneys of the toxin fed rats were more severely affected, as evidenced by mitochondrial swelling, vacuolation, ring forms, pleomorphism, and disintegration and loss of cristae. The intercellular junctions of PCT epithelial cells were widened and there was complete loss of microvilli. In liver, hepatocytes revealed pyknotic nuclei with increased heterochromatin, degranulation of rough endoplasmic reticulum and vacuolation of cytoplasm besides changes in mitochondria. The changes became more pronounced with increase in duration of toxicity. It may be concluded that OTA causes alternations primarily in mitochondria of renal PCT cells and liver hepatocytes.
来自期刊
Indian Journal of Veterinary Pathology (India)
ISSN : 0250-4758

书目信息

语言:
English
类型:
Summary
自何时收录于AGRIS:
2009
卷:
28
期:
1
起始页:
21
结束页:
24
所有题名:
"Ultrastructural changes in kidneys and liver in experimentally induced ochratoxicosis in wister rats."@eng
其它:
"Summary (En)"
"8 ill., 21 ref."
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书目信息

语言:
English
类型:
Summary
自何时收录于AGRIS:
2009
卷:
28
期:
1
起始页:
21
结束页:
24
所有题名:
"Ultrastructural changes in kidneys and liver in experimentally induced ochratoxicosis in wister rats."@eng
其它:
"Summary (En)"
"8 ill., 21 ref."