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Journal Article

Journal Article

Antiplatelet Activity of Gallic Acid and Methyl Gallate  [2004]

Lim, M.Y. (Chonbuk National University, Chonju, Republic of Korea); Park, Y.H. (Soonchunhyang University, Asan, Republic of Korea); Kim, M.K. (Chonbuk National University, Chonju, Republic of Korea); Lee, H.S. (Chonbuk National University, Chonju, Republic of Korea), E-mail: hoiseon@chonbuk.ac.kr; et al.

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The methanol extract obtained from Galla Rhois was investigated for its antiplatelet activity. The biologically active constituents of Galla Rhois were isolated by silica gel column chromatography and HPLC, and were characterized as gallic acid and methyl gallate by various spectral analyses. Gallic acid inhibited the platelet aggregation induced by collagen and by arachidonic acid with IC∧50 values of 5 and 94 μM, and methyl gallate inhibited the platelet aggregation induced by collagen and by arachidonic acid with IC∧50 values of 33 and 11 μM, respectively.

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Bibliographic information

Language:
English
Type:
Directory
In AGRIS since:
2006
Volume:
13
Issue:
6
Start Page:
806
End Page:
809
All titles:
" Antiplatelet Activity of Gallic Acid and Methyl Gallate "
Other:
" Summary(En) "
" 3 tables "
" 24 ref. "

From the journal

Food Science and Biotechnology

ISSN : 1226-7708