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Journal Article

Artículo de revista

Antiplatelet Activity of Gallic Acid and Methyl Gallate  [2004]

Lim, M.Y. (Chonbuk National University, Chonju, Republic of Korea); Park, Y.H. (Soonchunhyang University, Asan, Republic of Korea); Kim, M.K. (Chonbuk National University, Chonju, Republic of Korea); Lee, H.S. (Chonbuk National University, Chonju, Republic of Korea), E-mail: hoiseon@chonbuk.ac.kr; et al.

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The methanol extract obtained from Galla Rhois was investigated for its antiplatelet activity. The biologically active constituents of Galla Rhois were isolated by silica gel column chromatography and HPLC, and were characterized as gallic acid and methyl gallate by various spectral analyses. Gallic acid inhibited the platelet aggregation induced by collagen and by arachidonic acid with IC∧50 values of 5 and 94 μM, and methyl gallate inhibited the platelet aggregation induced by collagen and by arachidonic acid with IC∧50 values of 33 and 11 μM, respectively.

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Información bibliográfica

Idioma:
English
Tipo:
Directory
En AGRIS desde:
2006
Volumen:
13
Edición:
6
Página inicial:
806
Página final:
809
Todos los títulos:
" Antiplatelet Activity of Gallic Acid and Methyl Gallate "
Otro:
" Summary(En) "
" 3 tables "
" 24 ref. "

Publicación

Food Science and Biotechnology

ISSN : 1226-7708