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Journal Article

Artículo de revista

Effects of Amla (Phyllanthus embilica L.) Extract on Hair Growth Promoting  [2018]

Jang, S.H., Teazen Co., Ltd., Haenam, Republic of Korea; Kim, M.J., Teazen Co., Ltd., Haenam, Republic of Korea; Wee, J.H., Shinansan University, Ansan, Republic of Korea; Kim, J.T., Teazen Co., Ltd., Haenam, Republic of Korea; et al.

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This study aimed to determine that amla (Phyllanthus emblica L.) extract prevents and alleviates hair loss. We measured cell proliferative activity, 5alpha- reductase inhibitory, TGF-beta1 and DKK-1, IGF-1 and VEGF effect on human dermal papilla cells to investigate therapeutic effect of the amla extract. The cell proliferative activity in human dermal papilla cells was observed to be most prominent in the range of 50 μg/ml. Also, amla extract decreased the expression of 5alpha-reductase in a dose dependent manner in human dermal papilla cells. And IGF-1 and VEGF which were known to accelerate the differentiation and growth of human dermal papilla cells was increased by amla extract in a dose dependent manner. Taken together, these results suggest that amla extract has hair growth promoting effect and it may be a potent candidate for the prevention of hair loss.
Publicación
Korean Society for Biotechnology and Bioengineering Journal
ISSN : 1225-7117

Información bibliográfica

Idioma:
Korean
Tipo:
Directory
En AGRIS desde:
2019
Volumen:
33
Edición:
4
Página inicial:
299
Página final:
305
Todos los títulos:
"Effects of Amla (Phyllanthus embilica L.) Extract on Hair Growth Promoting"@eng
Otro:
"Summary(En)"
"2 tables"
"4ill., 29 ref."
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Información bibliográfica

Idioma:
Korean
Tipo:
Directory
En AGRIS desde:
2019
Volumen:
33
Edición:
4
Página inicial:
299
Página final:
305
Todos los títulos:
"Effects of Amla (Phyllanthus embilica L.) Extract on Hair Growth Promoting"@eng
Otro:
"Summary(En)"
"2 tables"
"4ill., 29 ref."