Water is becoming a limiting factor for wheat production in Pakistan. With rapid increase in population, competitive demands of water for domestic, industrial and recreational uses reduce its availability to agriculture sector. Production of major crops especially staple food like wheat needs to be increased in the country to fulfill food needs. This seems a challenging task under the existing situation with inefficient irrigation system, saline and polluted groundwater, and high cost of inputs, small land holdings, poor soil health and high yield gaps. Despite huge investments in water management and wheat research, food security is threatened mainly due to less focus on enhancing resource use efficiency, especially water. Ensuring food security requires a multi disciplinary approach with prime focus on improving the water use efficiency. It is suggested that utilizing an integrated approach that involves increase in the efficiency of irrigation system, efficient genotypes and efficient methods of water application at field level to improve the overall water use efficiency. A gradual shift shall be made from traditional irrigation methods to efficient methods of irrigation with the core idea of obtaining more crop yield per unit of water. Sensor and wireless technologies coupled with simulation models offer great prospect.