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In may 2007, the ULiège's Administrative Board (joined in June 2007 by the FUSAGx) decided to create an institutional repository and defined a strong institutional self-archiving policy to increase the visibility, accessibility and impact of the University's publications (ULiège mandate).

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The role of beta-casein variants in the induction of insulin-dependent diabetes in the non-obese diabetic mouse and humans  [1997]

Elliot, R.B.; Wasmuth, H.E.; Bibby, N.J. (University of Auckland (New Zealand). School of Medicine. Dept. of Paediatrics); Hill, J.P.;

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In the animal model the non-obese diabetic (NOD) mouse, casein is diabetogenic, whereas whey protein is not. The induction of diabetes by casein in the NOD mouse appears to be restricted to casein containing the A1 variant of beta-casein and possibly other variants of beta-casein which have a histidine at position 67 in the protein sequence. NOD mice fed A1 whole casein, but which also received naloxone in their drinking water, did not develop diabetes. Beta-casomorphin-7 which can only be released during digestion from those beta-casein variants containing His67 was inhibitory to immune cell function in NOD mice and prediabetic humans, but not in Swiss mice or normal humans.

Información bibliográfica

Idioma:
English
Tipo:
Summary
En AGRIS desde:
1999
Página inicial:
445
Página final:
453
Editorial:
International Dairy Federation
Todos los títulos:
"The role of beta-casein variants in the induction of insulin-dependent diabetes in the non-obese diabetic mouse and humans"@eng
Otro:
"Summary (En)"
"5 ill., 4 tables, 14 ref."
"Milk protein polymorphism. Proceedings of the IDF Seminar held in Palmerston North (New Zealand), February 1997, International Dairy Federation, Brussels (Belgium).- Bruxelles (Belgium): International Dairy Federation, 1997.- ISBN 92 9098 026 9. 480 p."
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Información bibliográfica

Idioma:
English
Tipo:
Summary
En AGRIS desde:
1999
Página inicial:
445
Página final:
453
Editorial:
International Dairy Federation
Todos los títulos:
"The role of beta-casein variants in the induction of insulin-dependent diabetes in the non-obese diabetic mouse and humans"@eng
Otro:
"Summary (En)"
"5 ill., 4 tables, 14 ref."
"Milk protein polymorphism. Proceedings of the IDF Seminar held in Palmerston North (New Zealand), February 1997, International Dairy Federation, Brussels (Belgium).- Bruxelles (Belgium): International Dairy Federation, 1997.- ISBN 92 9098 026 9. 480 p."