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Unique in the Czech Republic, the third greatest agricultural library all over the world concerning its significance and the extent of the collection, information sources such as 1.1 mil. of publications, created databases, and the extensiveness of provided services for the area of agricultural and food sector and the related fields. Access point to the complex series of specialised and branch information, publications and databases available online via internet. Deposit FAO library for the Czech Republic. National centre of the Internationa [...]

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Journal Article

Journal Article

Adipose stem cell combined with plasma-based implant bone tissue differentiation in vitro and in a horse with a phalanx digitalis distalis fracture: a case report  [2012]

Marycz, K., University of Environmental and Life Sciences, Wroclaw (Poland); Grzesiak, J., University of Environmental and Life Sciences, Wroclaw (Poland); Wrzeszcz, K., University of Environmental and Life Sciences, Wroclaw (Poland); Golonka, P., Equivet Horse Hospital, Gliwice (Poland);

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A horse suffering from an undetected hoof bone fracture was diagnosed three weeks after injury. The formation of callus tissue was detected at the fracture site. Standard orthopaedic screw application was augmented by a novel method, a combination of stem cells and plasma components. For experimental therapy, fat tissue and blood samples were collected from the patient to isolate stem cells and plasma proteins. The obtained and characterised mesenchymal stem cell population was applied to the wound area, together with an implant prepared from plasma, wrapped over the orthopaedic screw. Additionally, cells with implant were differentiated in vitro into bone tissue, to evaluate if cells could successfully produce extracellular matrix in such material. Three weeks after application, the hoof was significantly regenerated. The bone was completely rebuilt after three months. The in vitro experiment also gave positive results, with completely differentiated cells after three weeks. Our data show that enriching the standard orthopaedic material with mesenchymal stem cells adds therapeutic value to the treatment of refractory bone fractures.
From the journal
Veterinarni Medicina (Czech Republic)
ISSN : 0375-8427

Bibliographic information

Language:
English
Type:
Summary
In AGRIS since:
2013
Volume:
57
Issue:
11
Start Page:
610
End Page:
617
All titles:
"Adipose stem cell combined with plasma-based implant bone tissue differentiation in vitro and in a horse with a phalanx digitalis distalis fracture: a case report"@eng
Other:
"Summary (En)"
"20 ill."
"27 ref."
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Bibliographic information

Language:
English
Type:
Summary
In AGRIS since:
2013
Volume:
57
Issue:
11
Start Page:
610
End Page:
617
All titles:
"Adipose stem cell combined with plasma-based implant bone tissue differentiation in vitro and in a horse with a phalanx digitalis distalis fracture: a case report"@eng
Other:
"Summary (En)"
"20 ill."
"27 ref."