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Journal Article

Journal article

The Effect of Phyllantus emblica Linn on Type - II Diabetes, Triglycerides and Liver - Specific Enzyme  [2009]

Shamim A. Qureshi; Warda Asad; Viqar Sultana;

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The effect of aqueous fruit extract of Phyllanthus emblica Linn was studied on type-II diabetes, triglycerides (TG) and liver-specific enzyme, alanine transaminase (ALT). Our study showed that aqueous fruit extract, in a dose of 200mg/kg body weight, significantly decreased the blood glucose level after its intra-peritoneal administration in alloxan-induced diabetic rats (p<0.05). Almost similar decreased in glucose level was also observed by chlorpropamide, a known antidiabetic drug in a dose of 84 mg/kg. The aqueous extract also induced hypotriglyceridemia by decreasing TG levels at 0, 1, 2 and 4 hours in diabetic rats (p<0.05). In addition, the extract was also found to improve liver function by normalizing the activity of liver-specific enzyme alanine transaminase (ALT).

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Pakistan Journal of Nutrition

ISSN : 1680-5194