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Journal Article

Journal Article

Effects of Alcohol Consumption during Pregnancy and/or Lactation on the Morphology of Thyroid Gland in Male Wistar Rat Offspring  [2011]

J. E. Onu*, B. O. Oke1, P. C. Ozegbe1 and J. O. Oyewale2;

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The investigation was conducted to document the effect of alcohol on the morphology of thyroid gland of male rat offspring whose dams consumed alcohol during pregnancy and/or lactation. Seventy-five female rats divided into three groups, 1, 2, and 3, of 25 each and their offspring were used. Group 1 served as control (C), group 2 was exposed to alcohol during pregnancy and lactation (APL) while group 3 was exposed to alcohol during lactation only (AL). At day 35 and 49 postpartum 5 male rat offspring were randomly selected from the three groups and sacrificed. After the sacrifice, the thyroids were dissected out and their absolute and relative weights determined. Thereafter, the thyroid tissues were prepared for routine histological examination. The results of the investigation showed significant reduction (P<0.05) in the weights of the thyroid and thyroid follicles. There was also disorganization and desquamation of follicular cells. Our findings suggest that alcohol intake during pregnancy and/or lactation could be injurious to the thyroid glands of the offspring.
From the journal
Pakistan Veterinary Journal
ISSN : 0253-8318

Bibliographic information

Type:
Journal Article
In AGRIS since:
2012
Volume:
31
Issue:
4
Start Page:
357
End Page:
359
Publisher:
University of Agriculture, Faisalabad
All titles:
"Effects of Alcohol Consumption during Pregnancy and/or Lactation on the Morphology of Thyroid Gland in Male Wistar Rat Offspring"@eng
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Bibliographic information

Type:
Journal Article
In AGRIS since:
2012
Volume:
31
Issue:
4
Start Page:
357
End Page:
359
Publisher:
University of Agriculture, Faisalabad
All titles:
"Effects of Alcohol Consumption during Pregnancy and/or Lactation on the Morphology of Thyroid Gland in Male Wistar Rat Offspring"@eng