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The National Institute for Agricultural and Food Research and Technology (INIA) is an autonomous Public Research Organisation (OPI) of the State Secretariat of Research, Development and Innovation of the Ministry of Economy and Competitiveness. It's the only public research organisation of the National State Administration exclusively dedicated to agrifood and forestry research. INIA's mission, in coordination with the equivalent institutions of the Autonomous Regions is to contribute to continuous and sustainable progress through development [...]

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Journal Article

Journal Article

A CLA [Conjugated Linoleic Acid] enriched diet improves organ damage associated with the metabolic syndrome in spontaneous hypertensive rats  [2011]

Soto Rodríguez, I., Universidad Veracruzana, Veracruz (México). Facultad de Bioanálisis; Pulido Camarillo, E., Universidad Veracruzana, Veracruz (México). Facultad de Bioanálisis; Hernández Díaz, G., Instituto Tecnológico de Veracruz (México); Alexander Aguilera, A., Universidad Cristóbal Colón, Veracruz (México). Facultad de Medicina; et al.

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The purpose of this study was to provide evidence that dietary CLA can prevent the pathogenesis of metabolic syndrome in tissue structure, suggesting potential benefits in the onset of this syndrome. Wistar male spontaneous hypertensive rats (SHR), were classified into two groups that were fed a standard diet for eight weeks: one with 7.5% sunflower oil (V-SHR group), and the other with 6% sunflower oil and 1.5% CLA (CLA-SHR group). A control healthy group consisted of Kyoto-Wistar male rats fed the standard diet with 7.5% sunflower oil. The animals were sacrificed, and sections of liver, kidneys and aorta were fixed in 10% formaldehyde, and then stained with Hematoxylin and Eosin. Only in the V-SHR group, the stain of the aorta indicated irregular endothelial morphology; liver parenchyma was characterized by an infiltration of inflammatory neutrophils, fibrosis, thickening of the portal vein epithelium, hepatocyte hyperplasia and steatosis. The renal tissue of this group evidenced hyperplasia in the cells of the endothelial of Bowman´s capsule. Abnormal histological changes were not observed in either the control group or the rats fed with CLA, suggesting a protective role of CLA in the onset of metabolic syndrome.
From the journal
Grasas y Aceites (España)
ISSN : 0017-3495

Bibliographic information

Language:
English
Type:
Summary
In AGRIS since:
2011
Start Page:
49
End Page:
54
All titles:
"A CLA [Conjugated Linoleic Acid] enriched diet improves organ damage associated with the metabolic syndrome in spontaneous hypertensive rats"@eng
"Una dieta enriquecida con CLA [Ácido Linoleico Conjugado] mejora el daño a órganos asociados al síndrome metabólico en ratas hipertensas espontáneas."@esp
Other:
"Sumarios (En, Es)"
"Ilus., 4 tablas, 35 ref."
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Bibliographic information

Language:
English
Type:
Summary
In AGRIS since:
2011
Start Page:
49
End Page:
54
All titles:
"A CLA [Conjugated Linoleic Acid] enriched diet improves organ damage associated with the metabolic syndrome in spontaneous hypertensive rats"@eng
"Una dieta enriquecida con CLA [Ácido Linoleico Conjugado] mejora el daño a órganos asociados al síndrome metabólico en ratas hipertensas espontáneas."@esp
Other:
"Sumarios (En, Es)"
"Ilus., 4 tablas, 35 ref."