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Tsukuba Business-Academia Cooperation Support Center, Agriculture, Forestry and Fisheries Research Council Secretariat of the Ministry of Agriculture, Forestry and Fisheries, Japan (MAFF) was established in 1978 as Tsukuba Office and has been planning and operating various research facilities for supporting experimental research activities of research agencies, prefectural organizations and universities. The Tsukuba Business-Academia Cooperation Support Center is currently managing two centers, Agriculture, Forestry and Fisheries Research Infor [...]

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Journal Article

Journal Article

Effect of administration of indigestible dextrin prepared from corn starch on glucose tolerance in streptozotocin-diabetic rats  [1999]

Tashiro, M. (Mukogawa Women's Univ., Nishinomiya, Hyogo (Japan)); Kato, M.;

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The effect of indigestible dextrin obtained by heat-moisture treatment of HCl-adsorbed corn starch on glucose tolerance was investigated in rats with streptozotocin-induced diabetes. Rats were made diabetic by injecting 2-day-old neonates with 80 mg/kg streptozotocin. The diabetic rats showed obvious diabetic symptoms such as hyperglycemia, glucosuria and impaired glucose tolerance. From 57 days of age, the diabetic rats were given a diet containing a 4 % level of cellulose or a 5.7 % level of indigestible dextrin for 58 days. As a control, normal rats were given the diet containing cellulose. The glucose tolerance of diabetic rats fed the indigestible dextrin diet was significantly better than that of diabetic rats fed the cellulose diet. Oral sugar tolerance tests in healthy rats showed that administration of indigestible dextrin with sucrose suppressed the increase in the blood glucose level, whereas glucose did not. In vitro enzyme tests indicated that indigestible dextrin inhibited sucrase and maltase activities in the rat intestinal mucosa. The ameliorating effect of indigestible dextrin on glucose tolerance in the diabetic rats was considered to be due mainly to its alpha-glucosidase inhibitory activity
From the journal
Journal of Japanese Society of Nutrition and Food Science (Japan)
ISSN : 0287-3516

Bibliographic information

Language:
Japanese
Type:
Summary
In AGRIS since:
2001
Volume:
52
Issue:
1
Start Page:
21
End Page:
29
All titles:
"Effect of administration of indigestible dextrin prepared from corn starch on glucose tolerance in streptozotocin-diabetic rats"@eng
Other:
"Summaries (En, Ja)"
"2 tables; 6 fig.; 18 ref"
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Bibliographic information

Language:
Japanese
Type:
Summary
In AGRIS since:
2001
Volume:
52
Issue:
1
Start Page:
21
End Page:
29
All titles:
"Effect of administration of indigestible dextrin prepared from corn starch on glucose tolerance in streptozotocin-diabetic rats"@eng
Other:
"Summaries (En, Ja)"
"2 tables; 6 fig.; 18 ref"