Data provider:

Icon data provider

Tsukuba Business-Academia Cooperation Support Center, Agriculture, Forestry and Fisheries Research Council Secretariat of the Ministry of Agriculture, Forestry and Fisheries, Japan (MAFF) was established in 1978 as Tsukuba Office and has been planning and operating various research facilities for supporting experimental research activities of research agencies, prefectural organizations and universities. The Tsukuba Business-Academia Cooperation Support Center is currently managing two centers, Agriculture, Forestry and Fisheries Research Infor [...]

Journal Article

Journal article

Inhibitory effect of cassis [Ribes nigrum] extract against influenza virus infection  [2008]

Noguchi, A.(Shinshu Univ., Minamiminowa, Nagano (Japan)); Takeda, T.; Watanabe, T.; Yasui, H.;

Access the full text

Influenza virus (Flu) A type that breaks out every year has multiple subtypes and mutates the antigenicity every year. For this reason, it is hard for us to prevent the infection by vaccine. Furthermore, anti-Flu drugs have many troubles. On the other hand, it has been reported that flavonoids of black tea and green tea have an anti-Flu function. Therefore, we noticed cassis containing many flavonoids such as anthocyanin, and investigated an anti-Flu function using in vitro and in vivo tests. Cassis extract (CE) inhibited hemagglutination caused by Flu, and reduced accumulated symptom rate and improved the survival rate caused by nasal inoculation of Flu to mice. In addition, we fractionated, analyzed and investigated functional substance of CE. In the results, we found that anti-Flu functional substance of CE would be aromatic compounds without anthocyanins. These results indicate that CE has utilizable components to prevent infection of Flu A type.

From the journal

Journal of the Faculty of Agriculture - Shinshu University (Japan)

ISSN : 0583-0621