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Journal Article

Journal Article

Chemoprevention Effect of Polyozellus multiplex, a Wild and Edible Mushroom  [2000]

Hyun-Jeong Kim; Jung Han Dept. of Food Science and Technology, Keimyung University, Taegu 704-701 (Korea Republic);

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Methanol extract and its fractions of Polyozellus multiplex inhibited the growth of several tumor cell lines and its water fraction showed a higher cytotoxicity effect of the human gastric carcinoma cell, SNU668 than on the other cell lines. The glutathione S-transferase (GSH) content was decreased by MNNG treatment but increased by adding Polyozellus multiplex water fractions. Also the activities of GSH and superoxide dismutase were increased by more the treatment of Polyozellus multiplex water fractions than by N-methyl-N'-nitro-N-nitrosoguanidine (MNNG) alone. Polozellus multiplex water fraction caused a significant reduction in the proliferating cell nuclear antigen (PCNA) labelling index in the glandular stomach epithelium as compared with the value of MNNG alone.
From the journal
J. Korean Soc. Food Sci. Nutr.
ISSN : 1126-3311

Bibliographic information

Language:
Korean
Type:
Journal Article
In AGRIS since:
2001
Volume:
29
Issue:
1
Start Page:
161
End Page:
167
All titles:
"Chemoprevention Effect of Polyozellus multiplex, a Wild and Edible Mushroom"@eng
Other:
"Summaries (En, Ko)"
"illus;5 tables;1 ref;27"
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Bibliographic information

Language:
Korean
Type:
Journal Article
In AGRIS since:
2001
Volume:
29
Issue:
1
Start Page:
161
End Page:
167
All titles:
"Chemoprevention Effect of Polyozellus multiplex, a Wild and Edible Mushroom"@eng
Other:
"Summaries (En, Ko)"
"illus;5 tables;1 ref;27"