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Journal Article

Journal article

Anti-oxidative and Anti-cancer Activities of Extracting of Yacon  [2008]

Min, K.J. (Keimyung University, Daegu, Republic of Korea), E-mail:; Cheon, J.U. (Keimyung University, Daegu, Republic of Korea); Cha, C.G. (Keimyung University, Daegu, Republic of Korea);

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This study investigated the anti-oxidative and anti-cancer activities by extracting of Yacon by fraction with organic solvents. The content of total phenol was the highest by 45.53% in ethyl acetate fraction and the results of electron donating abilities were 65.20% (100 ㎍/mL), 91.81% (500 ㎍/mL) and 95.06% (1000 ㎍/mL) and those of nitrite scavenging abilities were 11.71% (100 ㎍/mL), 36.81% (500 ㎍/mL), 59.70% (1000 ㎍/mL) in ethyl acetate fraction, which were higher concentration than the control group. Xanthine oxidase inhibitory activities were 23.74% (100 ㎍/mL) and 43.41% (500 ㎍/mL) in low concentration, which showed higher activities than the control group. After measuring the growth inhibitory activities for cancer cells, it has been found that hexane fraction had the highest growth inhibitory activities by 23.75% (10 ㎍/mL), 34.67% (50 ㎍/mL), 54.21% (100 ㎍/mL) for SNU-1. Meanwhile, hexane fraction demonstrated high growth inhibitory activities by 41.38% (10 ㎍/mL), 50.53% (50 ㎍/mL), 60.91% (100 ㎍/mL) and butanol fraction had 17.05% (10 ㎍/mL), 43.87% (50 ㎍/mL), 62.99% (100 ㎍/mL) for HeLa. Therefore, it has been believed that there were peculiar properties of anti-oxidative and anti-cancer activities depending on each fraction. Furthermore, it has been expected that further studies on the development of functional food and concrete components depending on the components of each fraction to be conducted.

From the journal

Journal of Food Hygiene and Safety

ISSN : 1229-1153