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Journal Article

Journal Article

Anti-inflammatory Effect of MeOH Extract of Cibotium barometz in IFN-γ and LPS-stimulated Mouse Peritoneal Macrophage  [2010]

Lee, J.Y., Woosuk University, Samrye, Republic of Korea; Ko, S.H., Woosuk University, Samrye, Republic of Korea; Lee, Y.J., Woosuk University, Samrye, Republic of Korea; Lee, S.Y., Woosuk University, Samrye, Republic of Korea; et al.

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The rhizome of Cibotium barometz has been used for variety of bone disease as a traditional medicine. In the present study, we examined the antioxidant and anti-inflammatory activities of 85% methanol extract of C. barometz. C. barometz exhibited potent scavenging effect on 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical, superoxide radical and nitric oxide radical. In IFN-/γLPS-stimulated mouse peritoneal macrophage model, C. barometz suppressed nitric oxide production and IL-6 secretion dose-dependently. Moreover, C. barometz showed decreased iNOS and COX-2 expression without notable cytotoxicity. These results suggest that C. barometz may be an useful agent as an antioxidant and anti-inflammatory agent.
From the journal
Korean Journal of Pharmacognosy
ISSN : 0253-3073

Bibliographic information

Language:
Korean
Type:
Directory
In AGRIS since:
2013
Volume:
41
Issue:
2
Start Page:
108
End Page:
114
All titles:
"Anti-inflammatory Effect of MeOH Extract of Cibotium barometz in IFN-γ and LPS-stimulated Mouse Peritoneal Macrophage"@eng
Other:
"Summary(En)"
"1 tables"
"4ill., 49 ref."
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Bibliographic information

Language:
Korean
Type:
Directory
In AGRIS since:
2013
Volume:
41
Issue:
2
Start Page:
108
End Page:
114
All titles:
"Anti-inflammatory Effect of MeOH Extract of Cibotium barometz in IFN-γ and LPS-stimulated Mouse Peritoneal Macrophage"@eng
Other:
"Summary(En)"
"1 tables"
"4ill., 49 ref."