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Journal Article

Journal Article

Effects of Amla (Phyllanthus embilica L.) Extract on Hair Growth Promoting  [2018]

Jang, S.H., Teazen Co., Ltd., Haenam, Republic of Korea; Kim, M.J., Teazen Co., Ltd., Haenam, Republic of Korea; Wee, J.H., Shinansan University, Ansan, Republic of Korea; Kim, J.T., Teazen Co., Ltd., Haenam, Republic of Korea; et al.

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This study aimed to determine that amla (Phyllanthus emblica L.) extract prevents and alleviates hair loss. We measured cell proliferative activity, 5alpha- reductase inhibitory, TGF-beta1 and DKK-1, IGF-1 and VEGF effect on human dermal papilla cells to investigate therapeutic effect of the amla extract. The cell proliferative activity in human dermal papilla cells was observed to be most prominent in the range of 50 μg/ml. Also, amla extract decreased the expression of 5alpha-reductase in a dose dependent manner in human dermal papilla cells. And IGF-1 and VEGF which were known to accelerate the differentiation and growth of human dermal papilla cells was increased by amla extract in a dose dependent manner. Taken together, these results suggest that amla extract has hair growth promoting effect and it may be a potent candidate for the prevention of hair loss.
From the journal
Korean Society for Biotechnology and Bioengineering Journal
ISSN : 1225-7117

Bibliographic information

Language:
Korean
Type:
Directory
In AGRIS since:
2019
Volume:
33
Issue:
4
Start Page:
299
End Page:
305
All titles:
"Effects of Amla (Phyllanthus embilica L.) Extract on Hair Growth Promoting"@eng
Other:
"Summary(En)"
"2 tables"
"4ill., 29 ref."
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Bibliographic information

Language:
Korean
Type:
Directory
In AGRIS since:
2019
Volume:
33
Issue:
4
Start Page:
299
End Page:
305
All titles:
"Effects of Amla (Phyllanthus embilica L.) Extract on Hair Growth Promoting"@eng
Other:
"Summary(En)"
"2 tables"
"4ill., 29 ref."