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The Central Scientific Agricultural Library of the Russian Academy of Agricultural Sciences is a Bibliographic Center for Agricultural Science and Industry in Russia

Journal Article

Journal article

Estimation of mutagenic and antimutagenic properties of nanostructured phosphorus – component of complex fertilizer  [2019]

Degtyareva, I.A., Tatarstan Research and Development Inst. of Agrochemistry and Soil Science, Kazan (Russian Federation); Babynin, Eh.V., Kazan (Volga) Federal Univ. (Russian Federation); Motina, T.Yu.; Davletshina, A.Ya.; et al.

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Mutations are the first significant step in the carcinogenesis process, therefore, mutagenicity tests should be widely used to detect mutagens/carcinogens. The article presents the material on the estimation of the nanostructured phosphorite effectson the mutation process in the Salmonella typhimurium strains. In this study, strains S. typhimurium TA1535, TA1538 were used without metabolic activation. The data concerning the estimation of mutagenic properties of nanophosphate in the Ames test indicate that the test substance does not increase the frequency nor the mutation of base-pair substitutions at the TA1535 strain, no type of shift reading frames from strain TA1538. Consequently, nanofactory does not possess mutagenic activity. In addition, the data indicate the presence of antimutagenic activity against ethylme-thanesulfonate and 2,4-dinitrophenilhydrazine (38,0 and 60,0% at a concentration of 200.0 microgram/ml, respectively). Results of SOS-lux test using S. typhimurium TA1535/pDEW238 indicate the absence of DNA-damaging properties of nanophosphate. Thus, in the Ames and SOS-lux tests show the absence of mutagenic properties of nanostructured phosphorite, so it can be considered as safe for the environment and used for agro-industrial purposes, in particular, as a component of complex fertilizer.

From the journal

Agrochem Herald

ISSN : 0235-2516