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Institute of Agricultural Knowledge and Innovation - Slovakia, state enterprise is almost 50 years deparmently educational institution of the Ministry of Agriculture and Rural Development of the Slovak republic. It provides a broad portfolio of services mainly in the area of continuing vocational lifelong education, training and certification of Agricultural advisors, compiles specialized library collection, ensures effective and efficient access to information and information resources through information services and information technology. P [...]

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Journal Article

Journal Article

Comparative study of two natural antioxidants, curcumin and Curcuma longa extract  [2009]

Račková, L., Slovak Academy of Sciences, Bratislava (Slovakia). Institute of Experimental Pharmacology and Toxicology; Košťálová, D., Slovak Academy of Sciences, Bratislava (Slovakia). Institute of Experimental Pharmacology and Toxicology; Bezáková, L., Slovak Academy of Sciences, Bratislava (Slovakia). Institute of Experimental Pharmacology and Toxicology; Fialová, S., Slovak Academy of Sciences, Bratislava (Slovakia). Institute of Experimental Pharmacology and Toxicology; et al.

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The antioxidant capacities of curcumin and turmeric extract were determined and compared. Turmeric extract showed higher values of antioxidant power normalized to curcumin content (31.9%) in a majority of antioxidant assays than the curcumin standard. The particular half-maximal inhibitory concentration (IC50) values for curcumin were 2.34 micro g.ml sup(-1) in the 1,1-diphenyl-2-picrylhydrazyl (DPPH) test, and 0.21 mg.ml sup(-1) in the liposomal peroxidation assay in the extract, compared to IC50 = 3.33 micro g.ml sup(-1) and 0.343 mg.ml sup(-1) in the curcumin standard, respectively. Conversely, a significantly lower IC50 of curcumin (0.020 mg.ml sup(1)) for 12-lipoxygenase (LOX) inhibition was obtained than that of C. longa extract (2.95 mg.ml sup(-1)). The reactivity of the samples tested in the particular assays correlated well with the redox potentials of the model oxidants. In the liposomal system, the antioxidant activity may be influenced by the distribution processes at the phase interface. In conclusion, our results suggest that curcumin and its analogues may be decisive for the free radical-scavenging capacity of the turmeric extract.
From the journal
Journal of Food and Nutrition Research (Slovak Republic)
ISSN : 1336-8672

Bibliographic information

Language:
English
Type:
Summary
In AGRIS since:
2009
Volume:
48
Issue:
3
Start Page:
148
End Page:
152
All titles:
"Comparative study of two natural antioxidants, curcumin and Curcuma longa extract"@eng
Other:
"Summary (En)"
"1 table"
"2 ill., 23 ref."
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Bibliographic information

Language:
English
Type:
Summary
In AGRIS since:
2009
Volume:
48
Issue:
3
Start Page:
148
End Page:
152
All titles:
"Comparative study of two natural antioxidants, curcumin and Curcuma longa extract"@eng
Other:
"Summary (En)"
"1 table"
"2 ill., 23 ref."