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The National Agricultural Library is one of four national libraries of the United States, with locations in Beltsville, Maryland and Washington, D.C. It houses one of the world's largest and most accessible agricultural information collections and serves as the nexus for a national network of state land-grant and U.S. Department of Agriculture field libraries. In fiscal year 2011 (Oct 2010 through Sept 2011) NAL delivered more than 100 million direct customer service transactions.

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Journal Article

Journal Article

Antinociceptive activity of the methanolic extract of Kaempferia galanga Linn. in experimental animals  [2008]

Ridtitid, Wibool; Sae-wong, Chutha; Reanmongkol, Wantana; Wongnawa, Malinee;

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Kaempferia galanga Linn. (Zingiberaceae) presents many chemical constituents of the volatile oil extracted from the rhizome. The rhizome of Kaempferia galanga is used by people in many regions for relieving toothache, abdominal pain, muscular swelling and rheumatism. In this study we investigated the antinociceptive activity in mice and rats using acetic acid-induced writhing, formalin, hot plate and tail-flick tests. The extract at test doses of 50, 100 and 200mg/kg, p.o. clearly demonstrated antinociceptive activity in all tests. This activity was dose- and time-dependent. The extract administered at 200mg/kg, p.o. had a stronger antinociceptive effect than aspirin (100mg/kg, p.o.) but less than morphine (5mg/kg, s.c.). Naloxone (2mg/kg, i.p.) abolished the antinociceptive action of both morphine (5mg/kg, s.c.) and the extract (200mg/kg, p.o.) in a similar manner. In conclusion, the methanol extract of Kaempferia galanga markedly demonstrated the antinociceptive action in experimental animals. The antinociceptive mechanisms appear to be both peripherally and centrally mediated actions and the opioid receptors are probably involved. Therefore, our studies support the use in traditional medicine of Kaempferia galanga against pain caused by various disorders.
From the journal
Journal of ethnopharmacology
ISSN : 0378-8741

Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2013
Volume:
118
Issue:
2
Start Page:
225
End Page:
230
Publisher:
Amsterdam; New York: Elsevier
All titles:
"Antinociceptive activity of the methanolic extract of Kaempferia galanga Linn. in experimental animals"@eng
Other:
"Includes references"
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Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2013
Volume:
118
Issue:
2
Start Page:
225
End Page:
230
Publisher:
Amsterdam; New York: Elsevier
All titles:
"Antinociceptive activity of the methanolic extract of Kaempferia galanga Linn. in experimental animals"@eng
Other:
"Includes references"