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The National Agricultural Library is one of four national libraries of the United States, with locations in Beltsville, Maryland and Washington, D.C. It houses one of the world's largest and most accessible agricultural information collections and serves as the nexus for a national network of state land-grant and U.S. Department of Agriculture field libraries. In fiscal year 2011 (Oct 2010 through Sept 2011) NAL delivered more than 100 million direct customer service transactions.

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Journal Article

Journal Article

n-6 Docosapentaenoic acid is not a predictor of low docosahexaenoic acid status in Canadian preschool children  [2004]

Innis, S.M.; Vaghri, Z.; King, D.J.;

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Background: The n-3 fatty acid docosahexaenoic acid (DHA; 22:6n-3) is important for neural and visual functional development. In animals, 22:6n-3 deficiency is accompanied by increased docosapentaenoic acid (DPA; 22:5n-6), which suggests that the ratio of 22:6n-3 to 22:5n-6 could be a useful biochemical marker of low n-3 fatty acid status. The n-3 fatty acid status of preschool children has not been described, and data are lacking on whether low 22:6n-3 is accompanied by high 22:5n-6 in humans. Objective: We determined n-3 fatty acid status and investigated the relation between 22:6n-3 and 22:5n-6 in children. Design: In Canadian children aged 18-60 mo (n = 84), the n-3 and n-6 fatty acid status of erythrocyte phosphatidylethanolamine was measured, and dietary fat intake was estimated by using a food-frequency questionnaire. Results: The mean (± SEM) 22:6n-3 concentration in erythrocyte phosphatidylethanolamine among children was 3.06 ± 0.13 g/100 g fatty acids (5th-95th percentiles: 1.43-5.79 g/100 g fatty acids). Concentrations of 22:5n-6 increased with increasing 22:6n-3 concentrations in erythrocyte phosphatidylethanolamine (P < 0.01). Mean intakes of linoleic acid (18:2n-6), linolenic acid (18:3n-3), and trans fatty acids were 3.6 ± 0.2%, 0.7 ± 0.5%, and 2.0 ± 1.3%, respectively. Phosphatidylethanolamine 22:6n-3 and 22:5n-3 concentrations were inversely related to the intakes of 18:2n-6 and trans fatty acids, but not to those of total fat or n-3 fatty
acids. Conclusions: The concentration of 22:5n-6 is not a useful biochemical marker of low n-3 fatty acid intake or status in the membrane phosphatidylethanolamine of preschool children. High intakes of 18:2n-6 and trans fatty acids could compromise the incorporation of 22:6n-3 into membrane phospholipids.
From the journal
American journal of clinical nutrition
ISSN : 0002-9165

Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2013
Volume:
80
Issue:
3
Start Page:
768
End Page:
773
All titles:
"n-6 Docosapentaenoic acid is not a predictor of low docosahexaenoic acid status in Canadian preschool children"@eng
Other:
"Includes references"
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Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2013
Volume:
80
Issue:
3
Start Page:
768
End Page:
773
All titles:
"n-6 Docosapentaenoic acid is not a predictor of low docosahexaenoic acid status in Canadian preschool children"@eng
Other:
"Includes references"