Data provider:

Icon data provider

The National Agricultural Library is one of four national libraries of the United States, with locations in Beltsville, Maryland and Washington, D.C. It houses one of the world's largest and most accessible agricultural information collections and serves as the nexus for a national network of state land-grant and U.S. Department of Agriculture field libraries. In fiscal year 2011 (Oct 2010 through Sept 2011) NAL delivered more than 100 million direct customer service transactions.

Journal Article

Journal Article

Acute intake of phenolic-rich juice improves antioxidant status in healthy subjects  [2006]

García-Alonso, J.; Ros, G.; Vidal-Guevara, M.L.; Periago, M.J.;

Access the full text

The aim of this study was to evaluate the short-term effect of a phenolic-rich juice made from grape and berries on the antioxidant status of a group of healthy human subjects. After a 48-hour washout period, after an antioxidant-poor diet, 12 fasting subjects (6 men and 6 women) consumed a single dose (400 mL) of the juice. Blood was drawn before (baseline) and 1, 2, 4, and 6 hours post intake. Similarly, urine was collected before, 1, 2, 4, 6, and 24 hours post intake. Urinary excretion of phenolics increased and peaked at 2 hours after the intake and persisted up to 6 hours post intake. Accordingly, a slight increase was observed in serum lipid-bound polyphenols from 2 to 6 hours, which was associated with a significant decrease in serum lipid peroxidation products from 2 to 6 hours. In contrast, the serum protein oxidation increased between 1 and 4 hours post intake, and later fell back to baseline levels at 6 hours. Our data indicate that phenolics from the juice were bioavailable and able to bind with the lipid fraction of serum, therefore reducing lipid peroxidation. These observations lend weight to the widely reported anti-atherosclerotic activity of phenolic compounds. Last but not least, the most striking result of this research is the increase in protein oxidation associated with the juice intake. We think that such an effect could be due to a sugar-mediated oxidation mechanism. However, further studies are needed to elucidate the underlying me
chanism of this pro-oxidant response.

Access the full text


Bibliographic information

Journal Article
In AGRIS since:
26 issue 7
Start Page:
End Page:
All titles:
" Acute intake of phenolic-rich juice improves antioxidant status in healthy subjects "
" Includes references "

From the journal

Nutrition research

ISSN : 0271-5317