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The National Agricultural Library is one of four national libraries of the United States, with locations in Beltsville, Maryland and Washington, D.C. It houses one of the world's largest and most accessible agricultural information collections and serves as the nexus for a national network of state land-grant and U.S. Department of Agriculture field libraries. In fiscal year 2011 (Oct 2010 through Sept 2011) NAL delivered more than 100 million direct customer service transactions.

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Journal Article

Journal Article

Spectrophotometric and HPLC method for quantification of Loratadine on swabs for cleaning validation  [2013]

Rane, Shaligram S.; Padmaja, P.;

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Cleaning validation is a major challenge in multi-product pharmaceutical industries. UV spectrophotometric and HPLC methods have been developed and validated for determination of residual amount of Loratadine. Both methods were validated for linearity, range, accuracy, precision, and robustness. The limit of quantification was 1 mg L⁻¹ by UV spectrophotometric method and 0.5 mg L⁻¹ by HPLC method. A spike recovery study was done on a stainless steel (316 grade) plate and specific residual cleaning level (SRCL) was down to 6 μg 25.8 cm⁻². Recovery was found to be more than 70%. Both methods were simple, highly sensitive, precise, and accurate, and have potential of being useful for routine quality control.
From the journal
Toxicology and environmental chemistry
ISSN : 1029-0486

Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2014
Volume:
95
Issue:
2
Start Page:
232
End Page:
236
Publisher:
Taylor & Francis Group
All titles:
"Spectrophotometric and HPLC method for quantification of Loratadine on swabs for cleaning validation"@eng
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Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2014
Volume:
95
Issue:
2
Start Page:
232
End Page:
236
Publisher:
Taylor & Francis Group
All titles:
"Spectrophotometric and HPLC method for quantification of Loratadine on swabs for cleaning validation"@eng