Journal article
Anti-inflammatory Activity and Chemical Composition of Essential Oil Extracted with Supercritical CO2 from the Brown Seaweed Undaria pinnatifida
[2016]
Kang, Ji-Young;
Chun, Byung-Soo;
Lee, Min-Chul;
Choi, Jae-Suk;
et al.
Anti-inflammatory Activity and Chemical Composition of Essential Oil Extracted with Supercritical CO2 from the Brown Seaweed Undaria pinnatifida
2016
Kang, Ji-Young; Chun, Byung-Soo; Lee, Min-Chul; Choi, Jae-Suk; Choi, In Soon; Hong, Yong-Ki
https://doi.org/10.1080/0972060X.2014.989181
Essential oil extracted with supercritical CO ₂ fluid from the brown seaweed Undaria pinnatifida showed high anti-inflammatory activity. Optimal extraction with supercritical CO ₂ was observed at 45°C and 20 MPa. The essential oil was active against mouse ear inflammation induced by phorbol myristate acetate, with median inhibition concentration IC ₅₀ values of 87, 134, and 158 µg per ear for edema, erythema, and blood flow, respectively. The major component compounds were palmitic acid (26 %), 2-(9,12- octadecadienyloxy)-,(z,z)-ethanol (16 %), eicosa-5,8,11,14,17-pentaenoate (EPA; 13 %), and 5,7,11- eicosatrienoic acid (mead acid; 12 %). These findings are consistent with the claims that the seaweed U. pinnatifida can be used in remedies for inflammation-related symptoms.
[Journal of essential oil-bearing plants]
2016/US/US2016_2.rdf
Essential oil extracted with supercritical CO ₂ fluid from the brown seaweed Undaria pinnatifida showed high anti-inflammatory activity. Optimal extraction with supercritical CO ₂ was observed at 45°C and 20 MPa. The essential oil was active against mouse ear inflammation induced by phorbol myristate acetate, with median inhibition concentration IC ₅₀ values of 87, 134, and 158 µg per ear for edema, erythema, and blood flow, respectively. The major component compounds were palmitic acid (26 %), 2-(9,12- octadecadienyloxy)-,(z,z)-ethanol (16 %), eicosa-5,8,11,14,17-pentaenoate (EPA; 13 %), and 5,7,11- eicosatrienoic acid (mead acid; 12 %). These findings are consistent with the claims that the seaweed U. pinnatifida can be used in remedies for inflammation-related symptoms.
