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The National Agricultural Library is one of four national libraries of the United States, with locations in Beltsville, Maryland and Washington, D.C. It houses one of the world's largest and most accessible agricultural information collections and serves as the nexus for a national network of state land-grant and U.S. Department of Agriculture field libraries. In fiscal year 2011 (Oct 2010 through Sept 2011) NAL delivered more than 100 million direct customer service transactions.

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Journal Article

Journal Article

Effect of curcuminoids on oxidative stress: A systematic review and meta-analysis of randomized controlled trials  [2015]

Sahebkar, Amirhossein; Maciej Banach; Maria-Corina Serban; Sorin Ursoniu;

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The aim of the meta-analysis was to evaluate the efficacy of purified curcuminoids supplementation on plasma activities of superoxide dismutase (SOD), catalase and glutathione (GSH) and lipid peroxides as parameters of oxidative stress. Seven randomized controlled trials were finally selected for the meta-analysis. There was a significant increase of serum SOD activities after curcuminoids supplementation (weighted mean difference [WMD]: 1.15 U/mL, 95% confidence interval [CI]: 0.49–1.82, p = 0.0007). In a subgroup analysis, no significant effects was observed in the subset of studies administering curcuminoids for <6 weeks (WMD: 0.75 U/mL, 95%CI: −0.56–2.05, p = 0.26), but a significant increase of SOD activities was found with supplementation duration ≥6 weeks (WMD: 1.46 U/mL, 95%CI: 0.60–2.32, p = 0.0009). The curcuminoids significantly reduced serum lipid peroxides (WMD: −6.35 nmol/mL, 95%CI: −11.06 to −1.64, p = 0.008), increased GSH concentrations (WMD: 5.39 µg/mL, 95%CI: 1.17–9.60, p = 0.01), and catalase activity (WMD: 51.78 U/mL, 95%CI: 15.71–87.85, p = 0.005). This meta-analysis showed a significant effect of curcuminoids in elevating serum SOD and catalase activities, GSH concentrations, and reduction of serum lipid peroxides.
From the journal
Journal of functional foods
ISSN : 1756-4646

Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2017
Volume:
18
Start Page:
898
End Page:
909
Publisher:
Elsevier Ltd
All titles:
"Effect of curcuminoids on oxidative stress: A systematic review and meta-analysis of randomized controlled trials"@eng
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Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2017
Volume:
18
Start Page:
898
End Page:
909
Publisher:
Elsevier Ltd
All titles:
"Effect of curcuminoids on oxidative stress: A systematic review and meta-analysis of randomized controlled trials"@eng