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The National Agricultural Library is one of four national libraries of the United States, with locations in Beltsville, Maryland and Washington, D.C. It houses one of the world's largest and most accessible agricultural information collections and serves as the nexus for a national network of state land-grant and U.S. Department of Agriculture field libraries. In fiscal year 2011 (Oct 2010 through Sept 2011) NAL delivered more than 100 million direct customer service transactions.

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Journal Article

Journal Article

Anti-adipogenic effects of centipede grass extract in 3T3-L1 adipocytes and high fat diet induced obesity mice through activating adenosine monophosphate activated protein kinase  [2013]

Kim, Sokho; Oh, Myung-Hoon; Kwon, Jungkee;

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Eremochloa ophiuroides, as binominal nomenclature of centipede grass (CG) is native to China and Southeast Asia and is reported to contain several flavone C-glucosides and phenolic constituents, including maysin and luteolin derivatives, have been shown to have various beneficial properties. The aim of the present study was to investigate the effect of CG on adipocyte differentiation in 3T3-L1 cells and on obesity induced by a high fat diet (HFD) in mice. CG (100μg/ml) attenuated adipocyte differentiation of 3T3-L1 cells and reduced the accumulation of intracellular lipids through activation of 5′-adenosine monophosphate-activated protein kinase (AMPK), by down-regulating phosphorylation in AKT and glycogen synthase kinase (GSK) 3β. CG decreased levels of peroxisome proliferator-activated receptor (PPAR) γ and its target gene, fatty acid binding protein 4 (aP2). In addition, CG (5mg/kg) significantly suppressed body weight and fat content, and improved serum lipid concentration in obese mice. In conclusion, the present study suggests that CG have an anti-adipogenic effect through the activation of AMPK, which has the potential to prevent high fat diet induced obesity.
From the journal
Phytomedicine
ISSN : 0944-7113

Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2018
Publisher:
Elsevier GmbH
All titles:
"Anti-adipogenic effects of centipede grass extract in 3T3-L1 adipocytes and high fat diet induced obesity mice through activating adenosine monophosphate activated protein kinase"@eng
Other:
"Pre-press version Pre-press version"
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Bibliographic information

Language:
English
Type:
Journal Article
In AGRIS since:
2018
Publisher:
Elsevier GmbH
All titles:
"Anti-adipogenic effects of centipede grass extract in 3T3-L1 adipocytes and high fat diet induced obesity mice through activating adenosine monophosphate activated protein kinase"@eng
Other:
"Pre-press version Pre-press version"