Effects of partially hydrolyzed guar gum intake on human intestinal microflora and its metabolism
1994
Okubo, T. (Taiyo Kagaku Co. Ltd., Yokkaichi, Mie (Japan)) | Ishihara, N. | Takahashi, H. | Fujisawa, T. | Kim, M. | Yamamoto, T. | Mitsuoka, T.
The growth responses of a variety of human intestinal bacteria to partially hydrolyzed guar gum (PHGG) were investigated in vitro and in vivo. In an in vitro experiment, PHGG moderately enhanced growth of some bacterial strains including Bacteroides ovatus, clostridium coccoides, C. butyricum, and Peptostreptococcus productus. Effects of PHGG intake on fecal microflora,bacterial metabolites, and pH were investigated using mine healthy human volunteers. The count of Bifidobacterium spp. and the percentage of these species in the total count increased significantly during the PHGG intake periods. Among the acid-forming bacteria, Lactobacillus spp. also increased. The fecal pH and fecal bacterial metabolites such as beta-glucuronidase activity, putrefactive products, and ammonia content were significantly decreased by PHGG intake. Two weeks after the end of PHGG intake, the bacterial counts and their biological manifestations appeared to return to the former state
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