Effects of praziquantel and albendazole on Coenurus cerebralis in experimentally infected lambs
1998
Biyikoglu, G. (Central Veterinary Control and Research Institute Ankara (Turkey)) | Doganay, A. (Ankara Univ., Faculty of Veterinary Medicine, Ankara (Turkey))
In this study, effects of praziquantel and albendazole on Coenurus cerebralis were investigated. For this purpose, 5 dogs aged 2.5-3 months and 21 Akkaraman lambs aged 3-4 months were used. Three dogs were infected with Coenurus cerebralis protoscoleces, then the eggs collected from their feces were given to the lambs. Approximately 5500 eggs were given to each lamb. The lambs were divided into three groups consisting of 7 lambs each. The drug administration started at the first day of the occurance of the symptoms of coenurosis. Praziquantel a dose of 25 mg/kg for 3 days and albendazole a dose of 10 mg/kg for 14 days were given to the first and to the second group respectively. The third group was kept as control. Four lambs from the first group and 3 lambs from the second group were able to survive until the programmed necropsy date but the others died. Clinical recovery was observed in two sheep from both group until the day that necropsy was performed
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