Analytics of ivermectin residues in blood plasma and food of animal origin
2001
Cerkvenik, V. (Ljubljana Univ. (Slovenia). Veterinary Fac.)
Ivermectin is well appreciated due to small doses and high efficacy against endoand ectoparasites. Because of the actuality of this leading veterinary drug in terms of worldwide sales, numerous analytical methods for determination of its residues in body fluids, tissues and excreta, were published. In this article the developing and review of the respective ethodology is extensively presented. Methods using high performance liquid chromatography (HPLC) with fluorescence detection which enabled very low detectable limits are predominating. On the basis of literature, international cooperation and our own contribution also in our laboratory HPLC method, using fluorescence detection for determination of ivermectin residues in blood plasma and food of animal origin, was introduced. With optimisation of the procedure very low limits of detection in matrices in order of only 0.1 ppb were achieved what was classified among the best in the literature. The method is suitable for scientific research as well as routine purposes in the sphere of pharmacokinetics and food hygiene.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل University of Ljubljana