Comparison of the effect of simple and succussed homeopathic dilutions on systolic force: A study on isolated perfused rabbit's heart
2004
Erum, A. | Azeem, M.A. | Arifa, S. (Karachi Univ. (Pakistan). Dept. of Physiology)
The Homeopathic concept of potentization on dilution/succussion of a substance is considered mysterious for their normal and reverse effect on tissue. This concept of potentization is observed in the present study with differences in .the effect of simple and succussed dilutions on systolic force. For this purpose, both simple and succussed dilutions of Adrenaline were prepared serially, ranging from 10-3 to 10-36 for testing on the isolated perfused Rabbit's heart. Langendorff heart assembly was used to perfuse the heart and the systolic force was recorded on Oscillograph through isotonic transducer. Results demonstrated significant difference between SD & SUD at 10-3, 10-5, 10-6, 10-7, 10- 11, 10-27 & 10-36. Conclusively, this study confirms that there are differences in the effects of SD & SUD. While, potentization or reverse effect observed than normal has been found in- consistently throughout the range of dilutions used. Thus in- consistency expresses the instability of change in parent drug molecule.
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