Isolation of Urease Inhibitory Compounds from Arecae Semen
2005
Leem, M.J. (Dong-Wha Pharm. Ind., Anyang, Republic of Korea), E-mail: [email protected] | Ryu, J.M. (Dong-Wha Pharm. Ind., Anyang, Republic of Korea) | Jang, H.B. (Dong-Wha Pharm. Ind., Anyang, Republic of Korea) | Rho, Y.K. (Dong-Wha Pharm. Ind., Anyang, Republic of Korea) | Oh, S.J. (Dong-Wha Pharm. Ind., Anyang, Republic of Korea) | Lee, H.Y. (Dong-Wha Pharm. Ind., Anyang, Republic of Korea)
Urease plays an important role in the urea metabolism and the effect of urease activity on human and environment is enormous. For instance, urease acts as a virulence factor of the urinary and gastrointestinal tracts infections in human and animal, being involved in kidney stone formation, catheter encrusatation, pyelonephritis, ammonia encephalopathy, hepatic coma, and urinary tract infections. Widespread urease activity in soil induces a plant damage due to ammonia toxicity and pH increase.
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