Color-dilution alopecia in dogs
2005
Kim, J.H. (Cheju National University, Jeju, Republic of Korea), E-mail: kimjhoon@cheju.ac.kr | Kang, K.I. (The University of Georgia, Athens, GA, USA) | Sohn, H.J. (National Veterinary Research and Quarantine Service, MAF, Anyang, Republic of Korea) | Woo, G.H. (The University of Tokyo, Tokyo, Japan) | Hwang, E.K. (Sangji University, Wonju, Republic of Korea) | Jean, Y.H. (National Veterinary Research and Quarantine Service, MAF, Anyang, Republic of Korea)
Color-dilution alopecia is a relatively uncommon hereditary skin disease seen in "Blue" and other color-diluted dogs. This syndrome is associated with a color-dilution gene. The initial clinical signs are the gradual onset of a dry, dull and poor hair coat quality. Hair shafts and hair regrowth are poor, and follicular papules may develop and progress to frank comedones. Hair loss and comedo formation are usually most severe on the trunk, especially color-diluted area on the skin. Six cases of color-dilution alopecia are reported in 3 months to 10 years old dogs. The breeds of dogs are blue Doberman Pinscher, Miniature Pinscher, Dachshund, and Schnauzer. Grossly, extensive partial hair loss was seen on the skin. Histopathologically, the epidermis is relatively normal but may be hyperplastic.
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