Effect of Gastrodiae rhizoma Fractions on Serum Lipid Concentrations in Rats Fed with High Fat Diet
2005
Hong, H.D. (Korea Food Research Institute, Sungnam, Republic of Korea), E-mail: [email protected] | Kim, Y.C. (Korea Food Research Institute, Sungnam, Republic of Korea) | Keum, I.K. (Korea Food Research Institute, Sungnam, Republic of Korea) | Kim, S.S. (Korea Food Research Institute, Sungnam, Republic of Korea) | Kim, K.I. (Hyejeon College, Hongseong, Republic of Korea) | Han, C.K. (Korea Food Research Institute, Sungnam, Republic of Korea)
This study was carried out to investigate the effect of Gastrodiae rhizoma fractions on serum lipid profiles and atherogenic index (AI) in male S.D. rats fed a high fat diet supplemented with 10 : 2 : 1% (w/w) of lard, corn oil, and cholesterol during the entire 12-week experimental period. Forty-eight rats were randomly divided into four groups; A (low molecule), B (polysaccharide), C (protein) fractions of Gastrodiae rhizoma, respectively, and D (high fat diet as control). Body weight gain, diet intake and feed efficiency ratio did not differ significantly among the groups during the experimental period, but final body weight was on the average 44 g higher in control compared with the three groups of Gastrodiae rhizoma (A~C).
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