Pathogenicity of Paenibacillus polymyxa JB115 and single-dose toxicity of its culture broth containing β-glucan in rats
2007
Jung, H.K. (Daegu New Technology Agency, Daegu, Republic of Korea) | Kang, E.H. (Kyungpook National University, Daegu, Republic of Korea) | Chang, Zhi-Qiang (Kyungpook National University, Daegu, Republic of Korea) | Hong, J.H. (Daegu New Technology Agency, Daegu, Republic of Korea) | Kim, S.D. (Yeungnam University, Gyeongsan, Republic of Korea) | Park, B.K. (Jeonjinbio, Daegu, Republic of Korea) | Yun, H.I. (Chungnam National University, Daejeon, Republic of Korea) | Park, S.C. (Kyungpook National University, Daegu, Republic of Korea), E-mail: parksch@knu.ac.kr
This study was conducted to investigate the pathogenicity of Paenibacillus (P.) polymyxa JB115 and single oral dose toxicity of culture broth containing β-glucan (CBG-JB115) produced from P. polymyxa JB115 in Sprague-Dawely rats of both sexes for 14 days. After oral administration of P. polymyxa JB115 into rats, we could not find any abnormal clinical signs and variation in the body weight and temperature as compared with control group. We also investigated the acute toxicity of CBG-JB115. As the results, there were no clinical signs and variance in the body weight and temperature related with CBG-JB115 in comparison with the control group.
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