Antimicrobial activity of essential oil of Melissa officinalis L. (Lamiaceae) | Antimikrobna aktivnost etarskog ulja Melissa officinalis L. (Lamiaceae)
2003
Grujic-Jovanovic, S., Bioloski fakultet, Beograd (Serbia) | Simic, A., Bioloski fakultet, Beograd (Serbia) | Sokovic, M., Institut za bioloska istrazivanja Sinisa Stankovic, Beograd (Serbia) | Vukojevic, J., Bioloski fakultet, Beograd (Serbia) | Ristic, M.S., Institut za proucavanje lekovitog bilja Dr Josif Pancic, Beograd (Serbia) | Marin, P.D., Bioloski fakultet, Beograd (Serbia)
Commercial sample of essential oil of Melissa officinalis was analysed using GC and GC/MS. The main compounds identified in the essential oil were: citronellal (29.3%), limonen (8.84%), geranial (8.70%), alfa-terpineole (8.02%), alfa-terpinyl acetate (7.14%) and neral (5.68%). As test organisms the following micromycetes Penicillium ochrochloron, Aspergillus niger, Trichoderma viride and bacteria Bacillus subtilis, Staphylococcus epidermidis, Escherichia coli and Micrococcus luteus were used. Microdilution method on microplates 96-system was used for detection of minimum inhibition concentration (MIC), minimum bactericidal (MBC), and fungicidal concentration (MFC). Essential oil did not show antibacterial effect, but the oil of Melissa officinalis exhibited significant antifungal activity against tested micromycetes.
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