Effects of proliferation of CEF with ginsenoside and its derivatives | 中性红染色法检测人生皂苷及其衍生物对CEF增殖的影响
2009
Su Jianqing, Agricultural School of Liaocheng University, Liaocheng (China) | Chu Xiuling, Agricultural School of Liaocheng University, Liaocheng (China) | Wei Xubin, Jilin University, Changchun(China), College of Animal Science and Veterinary Medicine
[Objective] The research aimed to provide theoretical basis for studying anti-MDV mechanism of ginsenoside and its derivatives in vitro. [Method] Effects of ginsenoside and its derivatives on proliferation activity of chick embryo fibroblast (CEF) in vitro were determined by using neutral red dye absorption method. [Result] The results showed the proliferation effects of different drugs are not completely same, and are more obvious with low toxic drugs. Detected at different action times, the differences of OD values was biggest at 72 h when compared with normal control group, while there was no significant difference at 24 h. [Conclusion] Ginsenoside and its derivatives could promote the proliferation of CEF cells in medium as low concentrations, which have time-dependent characteristic.
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