EXPERIMENTAL PATHOLOGY OF ORNITHOBILHARZIA TURKESTANICUM IN SHEEP
2004
Ezzi, A., Razi Vaccine and Serum Research Institute, Tehran, Iran | Karimi, G.H., Razi Vaccine and Serum Research Institute, Tehran, Iran | Gholami, M.R., Razi Vaccine and Serum Research Institute, Tehran, Iran
To study the experimental pathology of Ornithobilharzia turkestanicum (O. turkestanicum) in sheep, 15 healthy sheep were chosen and classified into three groups at 5 each. Group 1 was dermal contacted with O.turkestanicum infected snail cercaria, group 2 was injected with the cercaria intra dermally and group 3 was considered as control. Clinical signs and egg counts were recorded continually. After one year they were sacrificed, autopsied and the tissues such as lung, liver, intestine and lymph nodes were examined grossly and microscopically. Granulomatous nodules were revealed in liver and intestine. Thrombophelebitis and the section of adult parasite within the veins were observed in liver tissue. Also the rosette formation around the egg larva was prominent at the center of the granuloma. By comparison two routes of applying the experiment we found out massive destruction of the liver and intestine was in group two rather than group one.
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