Effects of aspirin on the number of peripheral white blood cells and spleen eosinophils in guinea-pigs
2010
Turjačanin-Pantelić, D., University of Belgrade, Belgrade (Serbia). Faculty of Medicine | Pantić, I., University of Belgrade, Belgrade (Serbia). Faculty of Medicine | Pantić, S., University of Belgrade, Belgrade (Serbia). Faculty of Medicine | Garalejić, E., Faculty of Medicine, Belgrade (Serbia). University Clinic of Gynecology and Obstetrics Narodni Front | Jović, D., Faculty of Medicine, Belgrade (Serbia). University Clinic of Gynecology and Obstetrics Narodni Front | Arsić, B., Faculty of Medicine, Belgrade (Serbia). University Clinic of Gynecology and Obstetrics Narodni Front
Effects of lysine-acetylsalicylate, a soluble form of aspirin, on the number of eosinophil granulocytes in spleen imprints were investigated in outbred male guinea-pigs. The results suggest that small doses of aspirin could selectively increase blood eosinophil production or recruitment and that prostaglandins, could inhibit eosinophil production or migration in vivo.
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