Pathogenicity of the poxvirus isolated from ptarmigan against chicks and pigeons, distribution in chicks and efficacy of fowlpox vaccine.
1994
Nakashima N. | Ohishi K. | Hirayama N. | Nakamura M.
In 1986, at the Ohmachi Alpine Museum in Nagano Prefecture, a ptarmigan (Logopus mutus) which was fed artificially, died with pox-like lesions of the head skin and crop mucosa. We had isolated Avipoxvirus from the ptarmigan and named in Ohmachi strain. We studied the pathogenicity of the Ohmachi s. against chicks and pigeons, virus distribution in day-old-chicks, and efficacy of fowlpox vaccine against the Ohmachi strain. Day-old chicks which were challenged with the Ohmachi s. almost all died with severe pox-lesions and scabs on the inoculated site, eyelid and leg skin within 21 days. On the other hand, 16 weeks old chicks 7 days after challenge showed pox-leions only on the inoculated site, and the lesions disappeared within 28 days. However the Ohmachi strain did not show any pathogenicity against pigeons. The viruses were recovered from the inoculated site 2 days after challenge, and 4 days after challenge the viruses were recovered from the tanchea, heat, thymus, spleen, esophagus, crop, and proventriculus. After 17 days the viruses were recovered from the brain. We immunized day-old chicks with commercial fowlpox vaccines and 3 weeks after vaccination, these chicks were challenged with the Ohmachi s. and were protected against the challenge.
اظهر المزيد [+] اقل [-]الكلمات المفتاحية الخاصة بالمكنز الزراعي (أجروفوك)
المعلومات البيبليوغرافية
تم تزويد هذا السجل من قبل Wolters Kluwer