Kiselova, Y., Medical University, Varna , Laboratory of Nutrigenomics, Functional Foods and Nutraceuticals, Department of Biochemistry, Molecular Medicine and Nutrigenomics; Ivanova, D., Medical University, Varna , Laboratory of Nutrigenomics, Functional Foods and Nutraceuticals, Department of Biochemistry, Molecular Medicine and Nutrigenomics; Trendafilova, A.,, Bulgarian Academy of Science, Sofia . Institute of Organic Chemistry with Centre of Phytochemistry; Marinova, S., Medical University, Varna , Laboratory of Nutrigenomics, Functional Foods and Nutraceuticals, Department of Biochemistry, Molecular Medicine and Nutrigenomics; Zapryanova, Y,, Medical University, Varna , Laboratory of Nutrigenomics, Functional Foods and Nutraceuticals, Department of Biochemistry, Molecular Medicine and Nutrigenomics; Todorova, M., Bulgarian Academy of Science, Sofia . Institute of Organic Chemistry with Centre of Phytochemistry

Antioxidant activity and total phenolic content of fractions from selected Bulgarian medicinal plants | Antioxidačná aktivita a celkový obsah frakcií fenolov vo vybraných liečivých rastlinách Bulharska

2011

Kiselova, Y., Medical University, Varna (Bulgaria), Laboratory of Nutrigenomics, Functional Foods and Nutraceuticals, Department of Biochemistry, Molecular Medicine and Nutrigenomics | Ivanova, D., Medical University, Varna (Bulgaria), Laboratory of Nutrigenomics, Functional Foods and Nutraceuticals, Department of Biochemistry, Molecular Medicine and Nutrigenomics | Trendafilova, A.,, Bulgarian Academy of Science, Sofia (Bulgaria). Institute of Organic Chemistry with Centre of Phytochemistry | Marinova, S., Medical University, Varna (Bulgaria), Laboratory of Nutrigenomics, Functional Foods and Nutraceuticals, Department of Biochemistry, Molecular Medicine and Nutrigenomics | Zapryanova, Y,, Medical University, Varna (Bulgaria), Laboratory of Nutrigenomics, Functional Foods and Nutraceuticals, Department of Biochemistry, Molecular Medicine and Nutrigenomics | Todorova, M., Bulgarian Academy of Science, Sofia (Bulgaria). Institute of Organic Chemistry with Centre of Phytochemistry

The antioxidant activities (AOA) of crude methanolic extracts (CME) and its ethyl acetate (EAF), buthanol (BF), petroleum ether (PEF), chloroform (CF) and water fractions (WF) of eight Bulgarian medicinal plants were analyzed using the ABTS cation radical decolorizaton assay. The presence of compounds possessing antioxidant activity was identified in three fractions: in EAF of Fragana vesca, Rheum oficinale and Melissa officinalis, in BF of Cydonia vulgans, Hypencum perforatum and Origanum vulgare and in CME of Arctostaphylos uva-ursi. Total phenolic content (TPC) was also determined for each extract/fractions. EAF contained the highest TPC as compared to the other fractions for all species fol lowed by the BF for Arctostaphylos uva-ursi, Fragana vesca, Hypencum perforatum, Melissa officinalis and Origanum vulgare and by CME for Alchemilla vulgaris, Cydonia vulgans and Rheum officinale. AOA correlated positively to TPC of CME, BF and EAF, all of them showing a potential value as a source of natural antioxidants.

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