Anti-inflammatory and Anti-allergic Effect of Extracts from Organic Soybean
2011
Chung, E.K., Kyung Hee University, Yongin, Republic of Korea | Seo, E.H., Biowells, Chuncheon, Republic of Korea | Park, J.H., Biowells, Chuncheon, Republic of Korea | Shim, H.R., Biowells, Chuncheon, Republic of Korea | Kim, K.H., Gangwon-do Agricultural Research and Extention Services, Chuncheon, Republic of Korea | Lee, B.R., Hallym University, Chuncheon, Republic of Korea
This study was carried out to investigate the biological effects of organic soybean extracts. Cellular and molecular analysis was performed to determine anti-oxidative, anti-inflammatory, anti-apoptotic, and anti-inflammatory effects of soybean extracts. First, we obtained various solvent extracts of soybean such as water, ethanol, and methanol. Molecular and cellular analysis were performed with 0.1 mg/ml concentration of each solvent extracts. The results of anti-oxidative, anti-inflammatory and anti-apoptotic effects of organic soybean extracts were prominent. However, organic soybean extracts were not observed in anti-allergic effects determined by releasing histamine from rat mast cell line, RBL-2H3. Conclusively, organic soybean suppress inflammatory responses. In addition, organic soybean could be applied as a functional food ingredient for treatment of chronic inflammation, asthma, and atopic dermatitis with enhanced anti-inflammatory activities.
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