Beta-glucan feeding effect on biochemical and immune responses in vaccinated and non-vaccinated piglets against proliferative enteropathy
2013
Sorocinova, J., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Swine | Reichel, P., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Swine | Mudronova, D., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Dept. of Microbiology and Immunology | Novotny, J., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Ruminants | Link, R., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Swine | Leskova, L., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Ruminants | Smarzik, M., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Ruminants | Seidel, H., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Swine | Huska, M., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Swine | Macak, V., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Swine | Dobolyova, S., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Swine | Kovacocyova, K., University of Veterinary Medicine and Pharmacy, Kosice (Slovak Republic). Clinical Dept. for Swine
The aim of this study was to compare the results of active non-specific immuno-modulation in form of feeding food additive based on beta-glucan to pregnant sows and consecutive specific immuno-modulation by vaccination of their sucklings. Experimental sows were fed feedstuff with preparation on basis of beta-glucan at a 5% concentration from day 14 before parturition until the weaning of piglets; control sows were fed standard feedstuff only. Sucklings were vaccinated with a single dose of 2 ml of oral vaccine Enterisol Ileitis one week before weaning. Collection of biological material was done 3 x in sows and 5 x in sucklings. Post-vaccination examination of blood serum for antibodies against L. intracellularis in sucklings in experimental and control groups was negative, probably due to insufficiently long period of rejection of antibiotics-medicated feedstuff and by chlorinated water. With the exception of immunological profile, no essential changes were recorded in the dynamics of other indices of examined profiles in groups of sows in relation to immune-modulation. In groups of sucklings from sows fed beta-glucan supplemented feedstuff significant changes were determined for various indices compared with sucklings from sows fed standard foodstuff. This is the first similar study in pig herds in Slovakia.
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